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陈洁
发布时间:2019-04-15              阅读人数:402      作者:

陈洁,男,1989年出生,浙江余姚人,博士,2008年毕业于丽水学院生物科学(师范)专业,获理学学士学位,2015年毕业于上海海洋大学生物学专业,获理学硕士学位,2018年毕业于宁波大学渔业资源专业,获农学博士学位。2018年受聘加入丽水学院从事水产免疫分子生物学研究工作。已在Fish Shellfish ImmunolProbiotics AntimicroGene Expr Patterns等国内外期刊发表学术论文14篇,其中第一作者论文5篇。

主要研究方向:

1.水产动物抗菌肽功能研究

主持或参与科研项目:

1.香鱼LECT2诱导头肾造血干/祖细胞动员的机制,国家自然科学基金面上项目(31772876),25万元,2018.01-2019.12,第四

2.CXCL11/CXCR3.2信号途径调控香鱼单核/巨噬细胞M2型极化的作用和机制研究,浙江省自然科学基金重点项目(LZ18C190001),30万元,2018.01-2021.12,第四

代表性科研成果

论文:

1.Jie Chen, Yaoping Lv, Qingmin Dai, Zehui Hu, Ziming Liu, Jiheng Li. Host defense peptide LEAP-2 contributes to monocyte/macrophage polarization in barbel steed (Hemibarbus labeo)[J]. Fish & Shellfish Immunology, 2019, 87:184-192.

2.Jie Chen, Li Nie, Jiong Chen. Mudskipper (Boleophthalmus pectinirostris) hepcidin-1 and hepcidin-2 present different gene expression profile and antibacterial activity and possess distinct protective effect against Edwardsiella tarda infection[J]. Probiotics and Antimicrobial Proteins, 2018, 10(2): 176-185.

3.Ziming Liu, Jie Chen (co-firstauthor), Yaoping Lv, Zehui Hu, Qingmin Dai, Xiaoli Fan.Molecular characterization of a hepcidin homologue in starry flounder (Platichthys stellatus) and its synergistic interaction with antibiotics[J]. Fish & Shellfish Immunology, 2018, 83: 45-51.

4.Jie Chen, Xiaoyu Liu, Xiaohua Yao, Fei Gao, Baolong Bao, Dorsalfin development in flounder, Paralichthys olivaceus: Bud formation and itscellular origin[J]. Gene Expression Patterns, 2017, 25-26: 22-28.

5.Jie Chen, Qiang Chen, Xinjiang Lu, Jiong Chen. The protection effect of LEAP-2 on the mudskipper (Boleophthalmus pectinirostris) against Edwardsiella tarda infection is associated with its immunomodulatory activity on monocytes/macrophages[J]. Fish & Shellfish Immunology, 2016, 59: 66-76.